Postdoctoral Research Associate
Wellcome Trust-MRC Institute of Metabolic Science
Vacancy Ref. RG11199 Salary: £29,301 to £38,183
Limit of tenure applies*
We are seeking to appoint a Postdoctoral Research Associate in Genomics to join our internationally recognised team led by Professor Sadaf Farooqi, Cambridge, UK and funded by the Wellcome Trust. Our aim is to understand the genetic and molecular basis of obesity and diabetes (Wheeler et al. Nature Genetics 2013; Pearce et al. Cell 2013; www.goos.org.uk). The team participates in a wide variety of collaborative projects, performing genomic variation analysis, disease mutation discovery, RNA sequence analysis to explore new pathways involved in the pathogenesis of obesity and diabetes. Your work will have important implications for the clinical management of patients, including the development of better patient stratification and the identification of novel therapeutic targets.
To be considered for this position, you must:
- have a PhD in genetics or a closely related discipline
- have a high level of programming skills and experience applying statistical methods to genomic data
- have at least one first-author publication in a high-profile, internationally recognised journal
You should have experience with:
- the analysis of high throughput genomic data (genome wide association arrays, exome chip, exome/genome sequencing)
Responsibilities include analysis of high throughput genomic data including whole exome and genome sequencing from cohorts with obesity and thinness. You will have excellent communication and organisational skills as you will contribute to collaborative work with colleagues at the Wellcome Trust Sanger Institute and develop new external collaborations with partners in the NHS, Biotech and Pharmaceutical Industry. This position offers an ideal opportunity for a highly motivated scientist aiming to apply for Career Development Fellowships or Principal Investigator positions in the future.
Proposed start date: 6th March 2017 or as soon as possible thereafter.
Applications, including a full CV and a covering letter should be submitted on-line Ref. RG11199 on http://www.jobs.cam.ac.uk/
Closing date: 17th February 2017
* Fixed Term: The funds for this post are available for 24 months in the first instance.
SENIOR CLINICAL RESEARCH NURSE/NURSE MANAGER (Fixed Term)
Wellcome Trust-MRC Institute of Metabolic Science, Cambridge
Ref No: RG11252 Salary: £34,956 to £46,924
We are offering an exciting opportunity for a Senior Nurse to take on a key leadership role in a new purpose-built Metabolic Clinical Research Facility located at Addenbrooke’s Hospital, Cambridge. This post is equivalent to NHS Band 7-8a (depending on experience).
The Wellcome-Trust MRC Institute of Metabolic Science is one of the world’s leading Centres pioneering research in Metabolism. Our vision is to take scientific advances forward to develop new treatments for obesity and diabetes. Funded by a Strategic Award from the Wellcome Trust, we have established new, state-of-the-art Clinical Research Facilities with 8 beds dedicated to experimental medicine studies and trials in Obesity and Diabetes. The post-holder will be the Senior Nurse/Nurse Manager and will play a key role in establishing and running this Unit which is scheduled to open in April 2017.
We are looking to recruit a highly experienced Senior Nurse who will manage day-to-day clinical research activity on this Unit, develop and monitor clinical standards, providing visible clinical leadership and support for the research team. The role will involve supervision of a team of nurses and support staff as well as direct hands-on involvement in a number of research studies within a defined clinical area. Clinical studies involve recruitment of participants, obtaining informed consent, taking blood samples, performing specialist tests such as metabolic rate measurements, clamps, taking biopsies and administering trial drugs. Previous experience of working on a Clinical Research Facility, in a Trials Unit or in the Pharmaceutical Industry would be an advantage. Line management, scheduling and budget management experience is preferred.
You will be a registered nurse with current NMC registration, significant clinical experience in an acute care setting such as ITU, CCU, HDU or A&E and ideally clinical research experience. Training in advanced metabolic measurements will be given. Candidates should be highly motivated and effective communicators with a can do attitude and an eye for detail with a desire to develop their research skills. The successful candidate will work collaboratively with other Senior Research Nurses and research teams in the building and contribute to research governance procedures.
This is a full time University post funded by the Wellcome Trust. The post involves predominantly day-time shift patterns but may include occasional late-shifts and night duty. Proposed start date: as soon as possible.
Fixed Term: The funds for this post are available for 24 months in the first instance
Applications, including CV and a covering letter should be submitted on-line. Ref. RG11252 on http://www.jobs.cam.ac.uk/
Closing date: 22nd February 2017.