OTP gene controls expression of MC4R in the hypothalamus and mutations cause obesity in children
Within a given environment, some people put on weight very easily, whilst others remain thin. We aim to understand the key mechanisms that control body weight to inform the development of safe, effective weight loss interventions. We use genetic, molecular and clinical approaches to study cohorts of individuals with severe obesity and thinness.
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OTP gene controls expression of MC4R in the hypothalamus and mutations cause obesity in children
We would like to thank colleagues who refer patients to GOOS, research collaborators, funding bodies, former members of the GOOS team and the patients, families and volunteers who support our research.
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University of Cambridge Metabolic Research Laboratories
Level 4, Institute of Metabolic Science
Box 289, Addenbrooke's Hospital
Cambridge, CB2 0QQ
